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More importantly, the p53 expression level and p53 deacetylation rate were significantly increased in patients with nephrolithiasis and in CaOx crystal-treated HK-2 cells, as determined by analyzing the single-cell sequencing data and RNA-sequence data [279]
This highlights the complexity of GPCR activation, where downstream signalling is influenced by the interplay of multiple transducers that can interact with activated receptors (pleiotropic coupling), and can also be influenced by different trafficking profiles that alter the location of the receptor in the cell
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Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes
Effects of liraglutide and behavioral weight loss on food cravings, eating behaviors, and eating disorder psychopathology
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