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The standard markets reluctance to cover compounded versions underscores the necessity for experienced wholesale representation, particularly for excess and surplus (E&S) solutions
Activity must be appropriately loaded, not either absent or excessive: Complete rest prevents the mechanical stimulus that signals the tendon to rebuild with the appropriate architecture
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The reduced refolding by the chaperone is possibly due to the inability of these Syn variants to adopt the native tertiary inert state, causing prolonged chaperone engagement
