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The SELECT trial establishing semaglutides 20% reduction in major adverse cardiovascular events has converted GLP-1 receptor agonists from single-indication obesity drugs into foundational chronic disease therapeutics demanding continuous prescription renewal

In rodent models, GLP-1 receptor agonists have been shown to decrease both the consumption and the rewarding effects of opioids like heroin

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Healthcare professionals should provide thorough training on injection technique, including proper storage, needle attachment, dose selection, and disposal of sharps in appropriate containers (available from pharmacies or local authority schemes)

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It makes no therapeutic claims , no medical recommendations , and is provided strictly for research and educational purposes