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Research shows that its angiogenic and anti-inflammatory benefits may extend beyond the digestive system even in small doses

Safety is unknownand potentially problematic

While some preclinical studies with FGF21 and FGF21 analogs have suggested effects on bone turnover, clinical data have not demonstrated a consistent effect

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Adverse Reactions/Side Effects Generalized: Anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (see WARNINGS)

[9] Mao S, Huang J, Li J, Sun F, Zhang Q, Cheng Q, Zeng W, Lei D, Wang S, Yao J