I have been using my b12 ampoules 4 months now since expiry date on them ,Im down to twice weekly shots now and perfectly fine so I will continue to use them and if need be I will increase my frequency but as I said Ive been perfectly fine
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doi: 10.1186/s13054-015-0738-7 48 LiJ.ZhangL.WuT.LiY.ZhouX.RuanZ
However, alternating between slightly different spots around the inside ankle area helps prevent localized skin irritation from repeated injections in exactly the same location
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I don't see how you are getting that only 5mcg is lost daily: if you have injected say 1000 mcg of B12, most of it is peed out within a few days