semaglutide 6 months Medscape | (Wegovy) is associated with a 41% reduction in the risk for major adverse cardiovascular events (MACEs) within of 6 months on Semaglutide :

Most gastrointestinal side effects, including changes in bowel frequency, are most pronounced during initial treatment or dose escalation and typically improve significantly within 4-8 weeks as your body adapts to the medication

Many patients notice early improvements in appetite and energy within the first few weeks

Treatment Goals Aggressive goals may require higher doses or longer treatment duration

References How could Ozempic and its cousins change health care

"A systematic review, meta-analysis and meta-regression of protein intake in resistance-trained individuals." British Journal of Sports Medicine , 52(6), 376-384

I believe the psychological aspects of these medications deserve more attention than they typically receive