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Drug Metab Dispos : Epub ahead of print
The hyperglycemia-related increased proximal tubular sodium reabsorption results in lower sodium levels at the level of the macula densa increasing GFR via inhibiting TGF, further augmenting the amount of filtered and reabsorbed sodium with increased ATP demands
10.1096/fj.11-186460 FASEB J
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This relationship is established in foundational pharmacokinetic texts ( A common misconception is that long half-life drugs would accumulate indefinitely
Efficacy and safety of the new appetite suppressant, liraglutide: a meta-analysis of randomized controlled trials
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