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Status Not FDA-approved as of July 30, 2026
GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine, originally isolated by Loren Pickart from human plasma in 1973. The compound is one of the most extensively characterized small peptides in published research, with documented effects on collagen synthesis, glycosaminoglycan production, and approximately 4,000 human gene expression changes
When applied to your skin, it tells fibroblasts to increase collagen and elastin production, accelerates cell turnover for fresher skin, reduces inflammation and redness, and supports repair of UV and environmental damage
If you do consume alcohol, taking a dose of glutathione the following morning is a common strategy to help support your liver's recovery
Frequency depends on your goals and provider recommendations