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The phase 3 TRIUMPH-4 data showed these rates at 9 mg and 12 mg doses respectively: Nausea: 38.1% and 43.2% (vs 10.7% placebo) Diarrhea: 34.7% and 33.1% (vs 13.4% placebo) Constipation: 21.8% and 25.0% (vs 8.7% placebo) Vomiting: 20.4% and 20.9% (vs placebo) These numbers are higher than cagrilintide monotherapy across the board

If the issue lies with absorption, B12 shots or IV infusions are an effective alternative to oral supplements because they are administered via injection or intravenously, meaning they do not need to be absorbed through the digestive process

Verify the mass is 3,749 Da, not 3,400 Da this is the single most important check for cagrilintide

Side effects are rare but may include mild pain at the injection site, dizziness, or headaches