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So this study finding is an exciting step forward in our understanding of how these new medicines for obesity work, said study researcher Donal OShea, an endocrinologist at the University College Dublin and St Vincents University Hospital Dublin, in a statement

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These include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort

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Fibrosis improvement (secondary outcome) The study also looked at whether fibrosis improved by at least one stage: Liver fat reduction Participants also had significant reductions in liver fat content as measured by MRI, ranging from 42% to 57% reduction, depending on the dose