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Nei pazienti diabetici esiste un possibile segnale osservazionale, interpretato in larga parte come espressione della microangiopatia preesistente e della rapida correzione glicemica, pi che di una tossicit diretta del farmaco

An unacceptable margin for research protocols where target doses range from 100-500 micrograms

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In an unusual move, GLP manufacturers have asked for vision loss lawsuits to be consolidated in a group litigation called a multidistrict litigation