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BMC Biochem

Injectable semaglutide (Ozempic and Wegovy) is more effective for weight loss compared to the oral version (Rybelsus)

While these effects support weight loss, they can also trigger digestive discomfort, especially nausea and sometimes vomiting

Some guidelines recommend holding GLP-1 receptor agonists before procedures requiring sedation or general anesthesia to reduce the risk of aspiration, though specific recommendations may vary based on the procedure type and individual patient factors

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Insurance coverage varies widely and is changing rapidly