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GLP-1 directly regulates insulin secretion, while GLP-1 RAs have the potential to improve insulin sensitivity and glucose homeostasis by attenuating inflammatory pathways such as NF-B and the NLRP3 inflammasome signaling, thereby mitigating IR [40]

In an earlier blog I discussed a negative aspect Ozempic feet ( click here ) but there is another dermatological dimension to this class of drugs

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But for those who are overweight or obese, or those with diabetes, the science seems very favorable.

doi:10.1016/S0021-9258(18)46868-8