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How It Works Semaglutide mimics the GLP-1 hormone your body already produces, slowing digestion and helping your brain regulate appetite

Overuse or misuse of certain ingredients can lead to adverse effects such as skin irritation, allergic reactions, or even long-term damage

J Child Neurol 2003;18:552-4

Orforglipron significantly reduced HbA1c to 2.1% in a phase II clinical trial assessing its use in T2DM, while dulaglutide achieved 1.1% and a placebo achieved 0.43% [106]

Gastric bypass surgery already produces substantial increases in endogenous GLP-1 and other incretin hormones, which contribute significantly to post-operative weight loss and metabolic improvements