After 40 weeks, reduction of glycated hemoglobin (HbA1c) of -2.01, -2.24, -2.30 was seen in the 5 mg, 10 mg, and 15 mg tirzepatide respectively, compared to -1.86 reduction with 1 mg semaglutide
Fifty seven percent were male, 81% were White, 2% were Black or African American and 4% were Hispanic
As a leading retatrutide peptide , this compound allows researchers to investigate how multiple metabolic signaling pathways interact and influence physiological outcomes
On the other hand, there have been some case reports of drug-induced lupus associated with GLP1-RA use, in particular with semaglutide, so further study is warranted15
Will this data be compelling enough to move payers
Levels of this dipeptide can decline with age