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Cardiovascular safety DPP-4 inhibitors provide no benefits above the standard of care for people with established or high risk of atherosclerotic cardiovascular disease, heart failure or chronic kidney disease

The research also revealed that there is "a drive to prescribe, rather than making sure the patient is going to be safe in taking these medications and that the medication is going to be appropriate for them," Ramachandran said.

Even though GLP-1s are currently considered safe for a wide variety of users, substance abuse factors add a unique element that needs to be studied for safety

Is it really a miracle cure? Lebsack also interviewed McGills Jarry, who wrote an article in late 2023 well ahead of a rush of related online articles called The human lab rats injecting themselves with peptides. Jarry discussed the hard science, and lack thereof, of many popular stacks, as recapped below