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At this point, your body produces more insulin to clear the glucose from your blood, and when you over-produce insulin, you may experience an increased appetite and ultimately gain weight or have difficulty losing weight
In clinical practice, you often see that the most frequently cited endpoints in these assessments include: Cardiovascular events, such as major adverse cardiovascular events (MACE), myocardial infarction (MI), and all-cause mortality, which are critical for patients with diabetes and obesity
However, it's important to note that the most common complaints focus on slower results, higher pricing, and occasional customer service issues
Understanding where these two medications stand in that evolving landscape provides important context
Endocrinology 152 , 40724079 (2011)