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The largest of these trials (SURMOUNT-1) included over 2500 participants who experienced a mean weight loss of roughly 21% from baseline after 72 weeks at 15mg/weekly [19]
The RAI therapy, while effective, often causes hypothyroidism, and this requires lifelong replacement with thyroid hormones
Oral Rybelsus requires daily dosing while injected forms like Ozempic only need once-weekly shots
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