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acquired malignancy, pregnancy, OCP use, inflammatory disease, heparin-induced thrombocytopenia) Once a thrombus forms, it can propagate proximally (distal to proximal extension, increasing PE risk), embolize to the pulmonary arteries (PE see separate CDG), or undergo fibrinolysis (spontaneous resolution) or organization (becoming chronic/fibrotic)

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doi: 10.1007/s12035-013-8425-7 23