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Another possible explanation is that LC works at the hypothalamic level

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These features include reduced brain weight, a lower number and depth of cerebral sulci (the grooves on the surface of the brain), enlarged ventricles (cavities within the brain), and hypoplasia (underdevelopment) of the brainstem, cerebellum, frontal lobes, and temporal lobes

Therefore levels of free radical species are closely controlled by endogenous antioxidant molecules that quench their reactivity

J., Schaeffer, D

Abasic and oxidized abasic site reactivity in DNA: enzyme inhibition, cross-linking, and nucleosome catalyzed reactions