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If you are having B12 injections for a genuine deficiency, this is the context that helps you tell a settling-in reaction from a real problem
It will be difficult to engineer balanced agonism into a single small-molecule because the sequence hybridisation of the dual and triple peptide agonists has no obvious chemical analogue
Commonly reported side effects include: Headache Nausea Dizziness Injection-site pain Skin rash Itching Mild digestive problems Most are temporary, but serious allergic reactions can occur in rare cases
Sipe JD, Benson MD, Buxbaum JN et al (2016) Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 nomenclature guidelines
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The extended-release formulations offered more stable glucose regulation throughout the day and exhibited enhanced glycaemic control relative to their first-generation equivalents in direct comparison analyses (Nauck and Meier 2019)
Entry of exendin-4 into brain is rapid but may be limited at high doses
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