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These findings link low IGF-1 levels with certain measures of frailty, but the researchers werent able to prove a direct cause
The proven cardiovascular benefits of semaglutide, particularly the reduction in major adverse cardiovascular events demonstrated in the SELECT trial, also influence the decision for those with heart disease risk factors
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So not only are people putting their health at risk, they could also face very real legal consequences.' She added: 'As of 2025, Retatrutide is in Phase 3 trials, and if all goes well, it could be on track for approval between 2026 and 2027