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The enhanced hepatic mitochondrial activity in the context of TKT deficiency has been shown to be the result of increased phospholipid synthesis, particularly increased synthesis of phosphatidylcholine which represents the major phospholipid in the mitochondrial membrane

EClinicalMedicine 89:103558

Tochhawng, L., Deng, S., Pervaiz, S

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doi: 10.1007/s12011-012-9547-x 235 RootJ.MerinoP.NuckolsA.JohnsonM.KukarT