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This reaction and others present an opportunity for high concentrations of salicylic acid in the cell, which may also interact with cellular molecules and disrupt their activity

Specifically, the decrease in SIRT1 levels, inhibition of its activity, or generation of mutations that lower its activity have been linked to intestinal inflammation and colitis in human and rodent models (Caruso et al., 2014

Serious allergic responses, pancreatitis, gallbladder problems, hypoglycemia, kidney damage, and possible thyroid troubles are rare but possible side effects

Nutrition in Clinical Practice