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Reconstituted solution must be refrigerated
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Tirzepatide is administered as a once-weekly subcutaneous injection, with doses ranging from 2.5 mg to 15 mg depending on the indication and individual patient response
The vitamin B12 that I use is preservative free and highly absorbable methylcobalamin
For initial treatment of severe cases, 1 ampoule pair per day is given until the acute symptoms subside
One trial used 2000 g/day vitamin B 12 and demonstrated a mean difference of 680 pg/mL (95% confidence interval 392.7 to 967.3) in favor of oral vitamin B 12
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