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GLP-1: GLP-1(7-36) & GLP(9-36) GLP-1 is an endocrine peptide hormone synthesized in multiple locations including: 1) L-cells located in the intestinal mucosa, 2) -cells found in the pancreatic islet, and 3) central neurons residing in the nucleus of the solitary tract, a region regulating appetite and digestion (D'Alessio, 2016)
GABA regulates synaptic integration of newly generated neurons in the adult brain
This allows patients to consume fewer calories without the hunger pangs that derail traditional diets
The typical starting dose is 2.5 mg once weekly for four weeks, serving primarily as a tolerability dose rather than a therapeutic dose
We see this with other medications
That does not mean stacking is always necessary
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