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Why Anecdotes Are Unreliable Placebo effect : Expecting improvement creates real perceived improvement Selection bias : People who feel better are more likely to report Regression to the mean : Injuries often improve on their own Confounding variables : Diet, rest, other treatments No verification : Claims cant be independently confirmed Why Anecdotes Still Matter Anecdotal reports arent worthlessthey generate hypotheses worth testing

PMID 8591048

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But because the body can absorb a significant amount of hydroquinone compared with other ingredients (35% to 45%), its best to limit exposure (if any at all) during pregnancy