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In a rigorous clinical trial, the Southwest Oncology Group SWOG-8897 found that the MPO genotype of breast cancer patients undergoing chemotherapy was associated with a lower risk of recurrence, and a high-activity MPO genotype was related to a higher survival rate among women treated with cyclophosphamide [129]
Its practical advantage over earlier quinolinium analogues is permeability
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Tumor markers like PSA, CA-125, or CEA may be worth checking in individuals with relevant risk factors, though their usefulness for screening in healthy individuals remains debated
Malinda, K
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