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Recently, Altimmune reported interim data for its weekly injectable GLP-1/glucagon dual agonist (pemvidutide) in a Phase 2 trial--disappointing levels of discontinuations sent the stock tumbling 55%

doi:10.1371/journal.ppat.1011536 72

Indeed, - glucan is a non-digestible carbohydrate and acts as a substrate for improving colonic microbes as they are permitted to go through the small intestine due to their resistance to absorption (68, 69)

In modern research on the intrinsic GH axis, ipamorelin dominates due to this selectivity