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Mechanism of Action, Safety, and Efficacy Semaglutide exerts its effects through both central and peripheral pathways, replicating and enhancing the physiological actions of endogenous GLP-1 [35]
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Moreover, one phase 2 study conducted by Astrup et al
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In conclusion, this retrospective analysis underscores the intricate relationship between IBS subtype, sociodemographic determinants and specific GLP-1RA agents in shaping therapy discontinuation and switching patterns
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