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Acknowledgements We express our gratitude to the Vice-Chancellor for Research, Isfahan University of Medical Sciences for financial support through the scientific code 398979 and grant number 1989096
Participants received once-weekly subcutaneous injections of retatrutide at varying doses or placebo over 24 weeks, with a structured dose-escalation period built into the protocol to improve tolerability
GLP-1 is a hormone naturally released by your intestines after eating
This outcome reflects both the inherent difficulty of treating Alzheimer's disease and questions about whether a single neuroprotective mechanism, without addressing amyloid and tau pathology more directly, can be sufficient
Skeletal muscle inflammation and insulin resistance in obesity
For clients who feel isolated in their weight loss efforts, the coaching and community structure can be the difference that keeps them going
