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B vitamins, especially the methylated vitamins B6, B9, and B12, are also critical to help the body produce glutathione, as is magnesium

Regional and cellular gene expression changes in human Huntingtons disease brain

Renal protective effects have emerged as another important extra-hepatic benefit [15]

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HO-1, a critical antioxidant enzyme, enhances cellular defense against oxidative damage by catalyzing heme breakdown to produce Fe, carbon monoxide (CO), and biliverdin (35)