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Their effectiveness is supported by a large body of clinical research and real-world patient success
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GLP-1 receptor agonists work by: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood glucose levels without causing excessive hypoglycaemia Suppressing glucagon release from alpha cells, reducing hepatic glucose production Slowing gastric emptying , which prolongs the feeling of fullness after meals Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger and food intake These medications are administered via subcutaneous injection, typically once weekly or once daily depending on the specific formulation
Notably, zein-based nanocapsules demonstrated 3.3-fold greater oxidative stability compared to kafirin-based nanocapsules, a difference that aligns with their higher oil encapsulation efficiency (99)
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