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Reconstitution Best Practices Add bacteriostatic water slowly along the inner vial wall of the lyophilized peptide vial never inject directly onto the lyophilized powder cake, as this can cause local denaturation

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Identifying key molecules and pathways involved in this process can inform strategies to enhance ACL resilience and repair

This approach solved the challenge of peptide stability that limits many therapeutic peptides

PMID: 18331249 Wu G, et al

The challenge is straightforward but not simple: full-length BDNF protein is unstable, difficult to deliver, and cannot cross the blood-brain barrier in therapeutic form