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(14) Assisting with regular cell death

GH binds GHR via two binding sites (Site 1 and Site 2)

But does supplementing with it help to improve our immune function

No GHK-Cus mechanism targets tissue remodeling through fibroblast activation and matrix metalloproteinase regulation, which requires localized tissue concentration, not systemic plasma levels

Evidence snapshot: The strongest human evidence comes from a 2-year randomized controlled trial in 65 healthy older adults (Nass et al., 2008, Annals of Internal Medicine) showing sustained GH/IGF-1 increases and preserved fat-free mass, plus an earlier short-term human polysomnography study on sleep (Copinschi et al., 1997, Neuroendocrinology, PMID 9349662)

Protocol Used: 0.25 mg BPC-157 subcutaneous injection daily for 6 weeks, administered 2 inches proximal to Achilles insertion point, combined with eccentric heel drops and gradual return to running