FIGURE 2 Protection Against the Effects of Nervous System Aging on Degenerative Diseases Aging is the biggest cause of AD, mainly manifesting as the accumulation of A cell tangles, which eventually lead to memory (Selkoe and Hardy, 2016) and cognitive decline (Sarlus and Heneka, 2017)
Figure 2 More recently, a multiple hits theory has been proposed, with the addition of other pathogenic factors in NAFLD development: low-grade chronic inflammation, genetic and epigenetic mutations, and intestinal microbiota
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The patient meets the criteria for MCAS, but there is no relationship with a reactive disease, IgE-dependent allergy, or clonal or neoplastic mast cell activation