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In most cases with mild, isolated enzyme elevations, semaglutide can be safely continued with appropriate monitoring, though individual circumstances may warrant dose adjustment or discontinuation based on clinical judgment

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To view digital features for this article go to Introduction Obesity (defined as a body mass index [BMI] 30 kg/m 2 in adults [1]) is a major health concern in the USA [2] and is associated with multiple complications, including cardiovascular disease, type 2 diabetes, and osteoarthritis [3,4,5,6,7,8]

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Jett, L., et al

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But, as she says, 'it didn't change the fact that nothing worked.' Following this Knudsen got roped into the team's effort to improve a native GLP-1 peptide licensed from MGH

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2) This review completed by Wright et al investigates the development of small molecule AngIV analogs as potential treatments for AD and PD, two debilitating neurodegenerative conditions currently lacking effective disease-modifying therapies

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+ Polyphenols act synergistically

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