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Appetite suppression in both drugs is a secondary effect, not a primary therapeutic mechanism

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As regards the fibrinolytic process, an impairment of the binding and action of tissue-type plasminogen activator (t-PA) at the endothelial cell surface has been reported in the presence of homocysteine, which would thus inhibit endothelial-dependent fibrinolysis (Hajjar, 1993)

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These patterns warrant discussion with your GP, who can assess for underlying conditions such as diabetes, thyroid disorders, or other metabolic abnormalities through appropriate investigations