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Given the limited availability of pediatric data for dual and triple agonists, evidence from adult clinical trials was included where relevant to provide mechanistic insights and contextual understanding

Phygene, Fuzhou, China), which can readily enter cells and be cleaved by esterase to yield DCFH, a polar, nonfluorescent product

Table 2 summarizes the key methodological characteristics observed across these studies

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Despite limited big pharma involvement, venture funding is propelling new companies, potentially reshaping the industry landscape