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The medication is doing its job by promoting weight loss, but maintaining proper nutrition during that process is critical for keeping hair healthy

"Restoration of Blood Total Glutathione Status and Lymphocyte Function Following Alpha-Lipoic Acid Supplementation in Patients with HIV Infection." J Altern Complement Med 14.2 (2008): 139-46

Choosing a time is a matter of personal preference based on when these side effects are easier to manage

Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update

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For weight loss specifically, this is not a close comparison