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397,398 The KAITLIN phase 3 study compared anthracycline-based chemotherapy and then 18 cycles of T-DM1 plus pertuzumab (AC-KP) to taxane (threefour cycles) plus trastuzumab plus pertuzumab (AC-THP), adjuvant AC-KP did not result in statistically significant or clinically meaningful improvement in iDFS compared with AC-THP in patients with high-risk early breast cancer
Mansouri 2015)
NF-B, Nuclear Factor kappa-light-chain-enhancer of activated B cells
Both drugs can cause side effects like nausea and diarrhea, and they may increase the risk of serious conditions such as pancreatitis and thyroid cancer
4.3 Peroxiredoxin 2 Peroxiredoxins (Prxs
Yamada et al
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