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In this study, a large portion of patients reported multiple discontinuation reasons, reflecting the multifaceted challenges involved in GLP-1 RA use including tolerability, cost, access, and individual treatment goals
Zhang et al., 2025
Despite the use of these drugs, there was no increased incidence of congenital malformations in this cohort as compared to those on insulin
The TRIUMPH-4 Phase 3 trial showed 28.7% average weight loss with retatrutide 12 mg at 68 weeks, compared to 14.9% to 17.4% with semaglutide 2.4 mg across STEP trials
A mechanical side effect, like a bruise, happens because a needle was inserted into the skin
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