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Loss of SLC33A1 leads to GSSG accumulation and a hyperoxidizing ER environment, which impairs non-native disulfide resolution and causes misfolded protein accumulation
phenobarbital phenobarbital [4a] phenobarbital: contraindications, drug interactions, side effects contraindications & cautions: [1] Pregnancy
Am J Physiol Cell Physiol 285:C1537C1543 Azevedo-Martins AK, Lortz S, Lenzen S, Curi R, Eizirik DL, Tiedge M (2003) Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells
Additionally, Wang et al
Not specific to IGF-1 LR3 but pathway-relevant
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