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Very important, if confirmed and generalized. Conflict of interest: "I am a member of the OPEN-Spain expert group which, as can be seen on the website, receives funding from Novo Nordisk"
Magn Reson Imaging
While exact published numbers from SURMOUNT-5 continue to influence clinical practice, the general pattern confirms that tirzepatide at all doses produces greater weight reduction than even maximum-dose semaglutide
Moreover, a small clinical trial ( n = 127) that evaluated the GLP-1RA agonist exenatide compared to placebo as an adjunct to standard cognitive-behavioral therapy, reported that exenatide significantly reduced heavy drinking days and total alcohol intake in a subgroup of patients with obesity 12
If you would like to continue using a lower dose of Wegovy beyond the recommended four-week window, discuss your plans with a licensed clinician first
We will update this article when those results are published
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