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18 Personalized Titration : Companies are now patenting AI-based platforms that calculate the right dose based on a patients current and target weight, rather than following a fixed label schedule

References Coskun, T., Urva, S., Roell, W.C., Qu, H., Loghin, C., Kirchner, T., et al

Patients who may benefit from discussing LDN with a Provn provider include: Those with significant needle anxiety that GLP-1 therapy would compound Those with a history of pancreatitis or other GLP-1 contraindications Those with autoimmune conditions who havent responded to conventional weight management approaches Those experiencing chronic inflammation that may contribute to metabolic difficulty Those who have tried GLP-1 therapy without success or with intolerable side effects LDN is taken as a daily oral capsule at bedtime, avoiding the storage, injection, and travel logistics associated with GLP-1 injectable therapy

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"Treatment of complex regional pain syndrome: a review of the evidence"

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