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Guo S, Gu D, Yang Y, Tian J, Chen X

In pancreatic islet models, GLP-1R activation promotes beta-cell proliferation and reduces apoptosis under glucotoxic conditions

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[4] [5] For weight management, NICE technology appraisals (TA875 for Wegovy, TA664 for Saxenda) specify these treatments should be used within specialist weight management services (tier 3 or 4), with specific eligibility criteria, time-limited use, and defined stopping rules