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After initiation of BYETTA, observe patients carefully for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back and which may or may not be accompanied by vomiting)

But on hard outcomes VO2max, time to exhaustion, strength the evidence is inconsistent and the effect sizes are small

[19] [20] New or progressive neurological symptoms following nitrous oxide exposure warrant urgent medical assessment

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