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Abbreviations R/R DLBCL: Relapsed/Refractory Diffuse Large B-Cell Lymphoma R-CHOP: Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone ICIs: Immune Checkpoint Inhibitors PD-1: Programmed Cell Death Protein 1 PD-L1: Programmed Death-Ligand 1 ROS: Reactive Oxygen Species ER: Endoplasmic Reticulum ICD: Immunogenic Cell Death DAMPs: Damage-Associated Molecular Patterns CRT: Calreticulin HMGB1: High Mobility Group Box 1 ATP: Adenosine Triphosphate DCs: Dendritic Cells GSTs: Glutathione S-Transferases NBDHEX: 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol NAC: N-acetylcysteine MMP: Mitochondrial Membrane Potential WB: Western Blot IHC: Immunohistochemistry H&E: Hematoxylin and Eosin RNA-seq: RNA Sequencing BMDCs: Bone Marrow-Derived Dendritic Cells GzmB: Granzyme B IFN-: Interferon Gamma 4-PBA: 4-Phenylbutyric Acid References Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, et al
Statininduced Muscle Damage and Atrogin1 Induction Is the Result of a Geranylgeranylation Defect
might need to use a lot of PBS Delivering this in a nasal spray would require solid pH control and some carrier to make it sticky or it would just run out
The abundances of different cell types varied among samples were observed
