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We have previously shown that GSH (50 mg/kg/6 h) totally blocks OsG/oxidative stress-induced disarrangement of partitions of circulating immune cells and neutrophil/lymphocyte ratio 17
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Pharmacol Res 171:105782 Bendotti G, Montefusco L, Lunati ME, Usuelli V, Pastore I, Lazzaroni E et al (2022) The anti-inflammatory and immunological properties of GLP-1 receptor agonists
Increased intestinal permeability ("leaky gut") allows bacterial lipopolysaccharides (LPS) to enter the bloodstream, triggering systemic inflammation that impairs insulin signaling
In cultured H9c2 cells, GLP-1RAs attenuate the production of mitochondrial and intracellular reactive oxygen species (ROS) induced by methylglyoxal
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