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An in vitro study using HTR-8/SV neo (HTR-8) cells demonstrated that cigarette smoke exposure resulted in the accumulation of free iron and ROS, which subsequently caused lipid peroxidation and cell death

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Its main role is to neutralize free radicals generated in the body due to factors such as sun exposure, pollution and stress

Nutrient Deficiencies (Building Blocks Missing) Glutathione synthesis requires specific nutrients: Cysteine : From dietary protein (whey, eggs, poultry)-rate-limiting Glycine : Often deficient in modern diets (need 10-15g/day, most get 3-5g) Selenium : Cofactor for glutathione peroxidase (GPx) , the enzyme that recycles GSSG back to GSH B vitamins (B6, B9, B12): Required for methylation and sulfur metabolism Vitamin C : Recycles oxidized glutathione Deficiency in any of these impairs glutathione production or recycling [5]

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